What’s New – Scientists Spot More Migraine Genes

By Maureen Salamon

HealthDay Reporter

SUNDAY, June 10 (HealthDay News) — Two more genetic links to migraines have been discovered, a finding experts acknowledge won’t yet help those suffering from the throbbing headaches but may one day lead to new therapies.

Comparing the DNA of more than 2,300 patients afflicted with migraines without aura — the most common type — with 4,580 people in the general population, German and Dutch scientists spotted two gene variants associated with that migraine form. The research, authored by Arn van den Maagdenberg of Leiden University Medical Centre in the Netherlands, builds on a U.S. study released last year identifying three genes linked to migraines that suggested those inheriting any one of those genes had a 10 percent to 15 percent greater risk for the condition.

“Migraines are under-treated, under-recognized and under-diagnosed, especially with common migraines that don’t have any of the dramatic symptoms,” said Dr. Gayatri Devi, an attending neurologist at Lenox Hill Hospital in New York City. “A lot of times, people feel it’s their fault or that stress causes them . . . it’s nice to know there are genetic basis for illnesses and it’s not all in your head.”

The study is published online June 10 in the journal Nature Genetics.

Read more: http://www.philly.com/philly/health/HealthDay665593_20120610_Scientists_Spot_More_Migraine_Genes.html?cmpid=138896554#ixzz1xWS0R6je


More on this story –

Genetic indicators found for migraine sufferers
Herald Sun
SCIENTISTS have discovered four new genetic indicators that predispose people to one of the most common forms of migraine. The research, published in Nature Genetics, could lead to better drug development and treatment. The researchers carried out a …


Genes that predispose people to most common form of migraine identified
Zee News
Washington: After studied genetic data of more than 11000 people, researchers have found six genes that predispose people to the most common subtype of migraine without aura. Four of these genes are new and two of them confirm previous findings.


Search find genes related to migraine
ABC Online

Major pain European and Australian scientists say they have snared four more genes that highlight an inherited cause for common migraine. The genetic variants were spotted in a trawl through the DNA code of 4800 people with a history of “migraine …



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